Lab Team
CRAIGE LAB TEAM PHILOSOPHY
Exercise has remarkable potential. Our lab is driven to illuminate the potential of exercise to prevent multiple diseases by uncovering the molecular signals that drive metabolic responses. A foundational value for our lab in this endeavor is active curiosity. We investigate questions using our multi-perspective angles and dynamic experiences to uncover novel signaling pathways. Teamwork, in our lab, is more than just an important facet of project progress- we see each unique quality of our lab community as essential for success in advancing the scientific conversation.
Faculty
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Bio ItemSiobhan Craige, PhD , bio
Assistant Professor: Exercise metabolism; redox signaling in health and disease; vascular influence on diet and exercise
Siobhan completed her Ph.D. in the laboratory of Dean P. Jones at Emory University studying biological reduction/oxidation (redox) couples. Her postdoctoral training was conducted in the laboratory of John F. Keaney, Jr. at the University of Massachusetts Medical School, where she studied ROS signaling in the vascular endothelium. In August 2018, Siobhan began her independent laboratory in HNFE at VT to study redox signaling in exercise metabolism. Siobhan prioritizes mentoring in all aspects of her lab, and seeks out potential team members who are exceptionally curious, highly motivated, and excel when working in community with others.
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Bio ItemAdele Addington, PhD , bio
Lab Manager, Research Associate: Molecular signaling during exercise
As the Laboratory Manager / Research Associate for Dr. Craige, she assists students with their work, ensures the availability of materials and reagents, and manages general lab needs. She helps prepare research proposals and manuscripts for publication, establishes experimental protocols, and handles regulatory permissions for the lab. Additionally, she completes research projects aligned with the lab’s goals. With over 13 years of experience teaching undergraduate chemistry and biochemistry, and 16 years mentoring students in the lab, Adele works closely with them to ensure they excel in lab procedures and grasp the underlying theories behind each technique.
Adele is a life-long Hokie, earning her B.S. in Biochemistry (1990) and Ph.D. in Biochemistry (1994) from Virginia Tech. She enjoys collegiate football, basketball, and softball, and always supports the Hokies both at home and on the road. She enjoys traveling to other ACC and SEC softball venues and exploring the surrounding areas. When she's not traveling, Adele enjoys knitting, cooking, and spending time with her family.
Students
Jacob Bond is a 6th year Ph.D. candidate in the Translational Biology, Medicine, and Health program. Jacob seeks to understand how the hydrogen peroxide-producing enzyme NADPH oxidase 4 (NOX4) influences metabolism. He has had the privilege of working closely with Tencerova Lab (Institute of Physiology, Academy of Sciences of the Czech Republic) in order to unpack the role of NOX4 in changing the content of fat inside bone tissue, and how this differs in conditions of obesity between male and female mice.
One thing Jacob enjoys most about the Craige Lab is the supportive environment which encourages growth. Outside of the lab, you can find him at the gym, spending time in the sun, with his wife Jodie and friends, relaxing around a fire, and cuttin’ a rug. Following his graduate studies, Jacob is interested in pursuing a career which allows him to ask and answer scientific questions about vascular biology: why our arteries harden, and what is the magic of a healthy lifestyle that mitigates this.
Abhinav is currently a senior in Biochemistry and has recently started on the BS/MS Accelerated Master’s Track in the Craige Lab. Abhinav was involved in the inaugural CURLS cohort and has been a part of the Craige Lab since the Fall of 2022. During the summer of 2023, he continued his work in the Craige Lab as a Translational Obesity Undergraduate Research Scholar (TOUR), in which he characterized associated gene expression changes in C2C12 cells after treatment with a nitric oxide donor. Outside the lab, he is a peer mentor in the Biochemistry department, a brother of Alpha Chi Sigma, and a member of the badminton club. In his free time, he enjoys playing sports, going to the gym, and spending time with his friends.
Rebecca is a Ph.D. candidate with a concentration in molecular and cellular sciences. Rebecca, a native Michigander, received her Bachelors of Science in Genomics and Molecular Genetics & Human Biology from Michigan State University in 2020. Combining her passions in science and athletics, Rebecca is excited to research molecular response to exercise, specifically in skeletal muscle. Outside of the lab, some of her favorite things to do are cooking, Olympic lifting, and enjoying time with her friends and daughter.
Piere-Anne is a first-year doctoral student in HNFE, in the Molecular & Cellular Biology track. He joined Dr. Craige’s lab in August 2024. He got his bachelor’s degree in HNFE at Virginia Tech, with a focus on kinesiology. After obtaining his bachelor's degree, he worked as a Strength & Conditioning coach with both youth & professional athletes. Now, as a part of the lab his research, he will be focusing on the communication between endothelial cells and other tissues following exercise.